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Pharmactive Sets Gold Standard in Green Technology

MADRID, Nov. 7, 2019 /PRNewswire/ -- Pharmactive Biotech Products, S.L., the maker of affron®, the clean-label saffron extract, has optimized product quality and concentration with AFF® ON Cool-Tech, its new, natural proprietary extraction process that maintains peak freshness and purity. This process is gentle on the saffron plant – one of nature's most fragile – safeguarding the potent actives in the saffron essence.

Clean technology. Green product.

AFF ON Cool-Tech was specially designed, developed and patented by Pharmactive´s team of saffron extraction experts. "AFF ON Cool-Tech does not use harmful solvents, synthetics or additives of any kind," explains Jorge Rodríguez, Head of Production at Pharmactive, about the eco-friendly technique. "It generates very low waste and considerably reduces the impact on the environment, minimizing the carbon footprint. The AFF ON Cool-Tech process requires less industrial processing than other saffron extractors, lowering the energy consumed – and all in fewer steps."

AFF ON Cool-Tech produces the highest concentration of saffron-sourced Lepticrosalides® actives currently on the market, as tested and shown by HPLC-DAD (high-performance liquid chromatography with a diode-array detector). "Pharmactive is the first saffron actives supplier that can scientifically demonstrate how its products deliver outstanding beneficial/valuable properties at among the lowest recommended doses in the market (just 28 mg/day)," says Julia Diaz, Pharmactive's Marketing Manager. "This is a powerful indicator of AFF ON Cool-Tech's effectiveness."

Trusted saffron source

Saffron is among the most expensive botanicals in the world – literally worth more than its weight in gold – which makes counterfeiting common. Pharmactive cultivates saffron in its own fields in the exceptional Spanish Castilla-La Mancha region, where Crocus sativus L. has been grown and nurtured for centuries.  

Pharmactive collaborates with select saffron farmers, whose craft has been part of their cultural heritage for centuries. Their seasoned knowledge of saffron and how to optimally produce and harvest it – all without chemical fertilizers – is key to affron's unmatched quality. The art of saffron harvesting requires manual picking of choice stigmas during a brief daily window of time.

Food-to-fork processing, including local extraction, efficient transport and strategic storage, gives Pharmactive complete control and traceability of the supply chain to retain peak freshness and product authenticity.

From abundant field to potent yield

Affron saffron  is standardized to Lepticrosalides®, which is a complex of bioactive compounds that deliver affron's clinically demonstrated beneficial health and organoleptic attributes. Pharmactive conducts comprehensive quality control analyses to confirm affron purity and concentration.

Integrated extraction solution

Pharmactive reaps the benefits of an exclusive three-step, low-temperature production process that creates highly concentrated, potent affron with long-lasting actives stability – for up to 36 months.

  1. Prepare raw material: Hand-selected pure Crocus sativus L. stigmas are mixed with simple natural compounds to create a liquid solution.
  2. Extract and develop the concentrate: The extraction, concentration and purification of saffron stigmas at low temperatures and free of solvents is gentle on the actives.
  3. Dry the product: The proprietary cool-temperature drying technique further conserves the actives.

To protect the actives from outside elements such as air, humidity and contamination during storage, Pharmactive uses a composite structure made of exclusive materials.

Pharmactive: Technology in bloom

Rodríguez sums up the company's success: "Pharmactive's AFF ON Cool-Tech production expertise, as well as its distinct saffron insights and agronomy partnerships are vital to creating a superior saffron extract backed by clinical research targeting cognitive health." 

Pharmactive will introduce affron and at Vitafoods Asia in Singapore, Booth #I32, September 25-26, 2019. Affron® EYE, the affron product for eye health, is a finalist for the 2019 NutraIngredients-Asia Award in the Ingredient of the Year Healthy Aging category.

About Pharmactive Biotech Products, S.L.

Pharmactive Biotech Products, S.L., is a privately-owned company that develops and manufactures differentiated natural ingredients supported by scientific evidence. The company was founded by a group of entrepreneurs headed by Jean-Marie Raymond, who developed breakthrough solutions using the traditional Mediterranean saffron plant. With high standards and dedicated R&D investment, Pharmactive was the first company to introduce saffron extract for mood improvement. Pharmactive partners internationally with universities and research organizations to boost its R&D capabilities and generate new opportunities for its customers.

Visit us at CPhI 2019, Booth #41P12

For more information, contact:

Company contact:

Press Contact:

Pharmactive Biotech Products, S.L.


Julia Diaz, Head of Marketing

Liat Simha

Tel: +34 91 112 38 48

Tel: +972-9-9742893




Twitter: @Pharmactive_SP


Twitter: @LiatSimha

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SOURCE Pharmactive Biotech Products, S.L