You are here
Phase II Study of Interferon Gamma-1b Fails to Meet Primary Endpoint of Reversal of Fibrosis
"We have learned from this study that interferon gamma-1b is generally well tolerated in this patient population," said James Pennington, M.D., Executive Vice President of Medical and Scientific Affairs at InterMune. "We believe that earlier intervention in milder patients over a longer period of time may be necessary to demonstrate efficacy."
About interferon gamma-1b (Actimmune(R))
Interferon gamma is a naturally occurring protein that stimulates the immune system. InterMune markets Actimmune for the treatment of two life-threatening congenital diseases: chronic granulomatous disease and severe, malignant osteopetrosis. Presently, InterMune is conducting a Phase III study of interferon gamma-1b in idiopathic pulmonary fibrosis (IPF), and a Phase III study of interferon gamma-1b in ovarian cancer. The most commonly observed side effects are flu-like symptoms, including fever, headache and chills. Physicians and patients can obtain additional prescribing information regarding Actimmune, including the product's safety profile, by visiting www.actimmune.com.
Source: InterMune, Inc.