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P&T July 2016

Features

Aims for Greater Use of Pharmacists, Cost Savings, and Better Outcomes

A new test model starting in five regions in 2017 seeks better integration of pharmacists into the Medicare Part D Medication Therapy Management program, which has severely underperformed since the Part D benefit took effect in 2006.

Part 1: Childhood Vaccinations

Childhood vaccination is one of the most effective public health strategies to control and prevent disease, but some parents decline or delay vaccinating their children. A variety of measures have been suggested to overcome vaccine noncompliance.

National treatment guidelines for bacterial meningitis were published in 2004, but no assessment of their use has been reported. In retrospective chart reviews at two hospitals, recommended antibiotic regimens were given to 52.6% of the 38 patients.

In a retrospective review, the prevalence of delirium did not differ among intensive care unit patients who received either dexmedetomidine or propofol alone for 24 hours or more. Propofol was linked with more coma and shorter hospital stays.

Departments

Medication Errors

We all have a role in preventing fentanyl patch tragedies

Prescription: Washington

HHS walks a middle ground in final nondiscrimination rule

Approvals, new indications, regulatory activities, and more

Defibrotide sodium (Defitelio) for hepatic veno-occlusive disease; emtricitabine/tenofovir alafenamide (Descovy) for human immunodeficiency virus infection; and infliximabdyyb (Inflectra) for Crohn’s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis

Drug Forecast

Brexpiprazole (Rexulti): a new monotherapy for schizophrenia and adjunctive therapy for major depressive disorder

Meeting Highlights

We report on key Digestive Disease Week sessions that focused on hepatitis C virus and Clostridium difficile infection, colonoscopy preparation, irritable bowel syndrome, and Crohn’s disease.

Meeting Highlights

We review major American Society of Clinical Oncology sessions on breast, pancreatic, ovarian, skin, and brain cancers and multiple myeloma.