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P&T November 2016


Medication Use Will Be Integrated Into Marketplace Plan Risk Adjustments

The Centers for Medicare and Medicaid Services’ addition of drug utilization categories to the risk-assessment process aims to make scores more sensitive and accurate, which may help stem the exodus of companies from the marketplace.

After incorporating system formulary-related information and related resources into a single commercial formulary management tool, one health system increased pharmacist end-user satisfaction and overall use of formulary-related information.

Rapid-acting bronchodilators, systemic corticosteroids, and antibiotics are among the keys to managing exacerbations of chronic obstructive pulmonary disease. Preventing exacerbations should also be a component of therapy for the disease.

To address the need for updated pregnancy risk categories, the Food and Drug Administration published a final rule in 2014. The authors review the changes the rule makes, its implementation schedule, and its potential clinical impact.

Researchers surveyed pharmacists’ preparedness for the state’s medical cannabis program and found that more training and education on the regulatory and clinical aspects of cannabis were needed in preparation for their work with patients.


Medication Errors

Using a saline flush “site unseen” could lead to a wrong-route error

Prescription: Washington

Can the FDA do more to encourage orphan drug development?

Approvals, new indications, regulatory activities, and more

Calcifediol (Rayaldee) for secondary hyperparathyroidism in adults with chronic kidney disease; dasabuvir/ombitasvir/paritaprevir/ritonavir (Viekira XR) for hepatitis C virus infection; and lixisenatide (Adlyxin) for type-2 diabetes

Drug Forecast

Perampanel (Fycompa): a review of clinical efficacy and safety in epilepsy