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P&T January 2016

Features

The Pressure Is on P&T Committees to Monitor Utilization

The agreement between Harvard Pilgrim and Amgen on a “pay for performance” deal involving evolocumab could encourage other manufacturers, health plans, and policy-makers to press for value-based pricing as drug costs continue to escalate.

Use of sodium polystyrene sulfonate (SPS) dominates the long-term treatment of hyperkalemia, but two new agents, sodium zirconium cyclosilicate and the recently FDA-approved patiromer, may offer potential advantages compared with SPS.

Coupled with administration support of an action plan that promotes quality of care and a culture of safety, the Medication Error Prioritization System (which automates parts of error review) has led to improvements for an integrated health care system.

Departments

Medication Errors

Community liaison programs to cut hospital readmissions

Prescription: Washington

FDA deluged with opinions on biosimilar naming plans.

FDA approvals, drug indications, and updates

Elotuzumab (Empliciti) and ixazomib (Ninlaro) for some multiple myeloma patients; Fluad (influenza vaccine, adjuvanted) for immunization of persons 65 years of age and older; and osimertinib (Tagrisso) for certain non–small-cell lung cancers

Drug Forecast

Alirocumab (Praluent): first in the new class of PCSK9 inhibitors

Meeting Highlights

Key sessions at the meeting covered the effects and relationships of early remission, weight, corticosteroids, and anti-tumor necrosis factor agents in rheumatic diseases.

Pipeline Plus

Analysts foresee substantial growth in the multiple myeloma market in the next decade, driven mainly by the monoclonal antibodies elotuzumab and daratumumab.