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P&T November 2015


Letter to the Editor
Health Care & Law

Although the health care marketplace is changing rapidly, some things have not changed, including the need for P&T committees and organizations’ management to beware of ethical and legal issues such as discrimination, quotas, and understaffing.

Part 4: Treatment of Motor Complications

Parkinson’s motor complications include wearing-off, a delayed or absent response to carbidopa/levodopa therapy, freezing of gait, dyskinesias, and dystonias. Treatment may include medication adjustments, such as increased dopaminergic stimulation.

Up to 70 million U.S. adults have chronic sleep and wakefulness disorders. Therapies may include prescription medications approved by the Food and Drug Administration, off-label treatments, over-the-counter drugs, and herbal therapies.

Meeting Highlights

The European Cancer Congress, which attracts a range of European cancer groups, reflected intense interest in immunotherapies. we review key sessions, including three on the anti-programmed death-1 agent nivolumab, each in a different disease setting.

Pipeline Plus

Future therapies for growth hormone deficiency are expected to include long-acting formulations that may encourage increased use of and adherence to these products.


Medication Errors

The index of suspicion: red flags warn of safety threats.

Prescription: Washington

Pharmacies wrestle with the FDA’s new drug-tracing rule.

FDA approvals, drug indications, and updates

Evolocumab (Repatha) for patients with hypercholesterolemia whose condition has not been controlled by statins and other therapies; trifluridine/tipiracil (Lonsurf) for metastatic colorectal cancer; and blood coagulation factor VIII (Nuwiq) for adults and children with hemophilia A

Drug Forecast

Afrezza (insulin human) inhalation powder: a new inhaled insulin for the management of type-1 or type-2 diabetes mellitus