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P&T September 2012


Part 1: Emerging Concepts

Nanoparticles may soon be used to transport diagnostic and therapeutic drugs to targeted sites not normally accessible, thereby improving treatment and reducing costs. Further research is still needed to establish the efficacy and safety of these nanomaterials.

A retrospective chart review revealed that patients receiving alvimopan after bowel surgery had faster recovery times, better surgical care, and lower costs of care compared with patients who did not receive the drug.


Letters to the Editor
Medication Errors
Automated dispensing cabinets have had a mixed record on improving drug safety.
Prescription: Washington
Pharmacists will need to become well versed in the FDA’s REMS for opioids.

FDA approvals, drug indications, and updates

Lorcaserin (Belviq), an appetite suppressant; pertuzumab (Perjeta) for HER-2– positive metastatic breast cancer; MenHibrix vaccine for meningococcal infections and influenza; icosapent ethyl (Vascepa) for reducing triglycerides; and aclidinium inhalation (Tudorza) powder for bronchospasm in COPD

Drug Forecast

Ipilimumab (Yervoy) for metastatic melanoma