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P&T October 2012
The growing abuse of toxic stimulants known as “bath salts” can cause psychosis and possibly death. Raising awareness of the dangers through patient counseling and community outreach programs will be important—especially efforts aimed at young people.
A 70-year-old man with a history of fibromyalgia, type-2 diabetes mellitus, hypercholesterolemia, and chronic low back pain presented to the emergency department with altered mental status, limb weakness, twitching, and slurred speech. The authors sought to determine whether his rhabdomyolysis resulted from an adverse reaction associated with pregabalin and simvastatin.
Although many nanotherapeutic and nanodiagnostic agents are in use and have the potential to improve health care, many barriers have impeded the development and availability of these products. Despite these impediments, it is expected that nanomaterials will become an integral part of mainstream medicine.
FDA approvals, drug indications, and updates
Truvada for HIV prevention, Xtandi for metastatic castration-resistant prostate cancer, and Marqibo, a vincristine liposome injection for acute myelogenous leukemia