Although selective serotonin reuptake inhibitors (SSRIs) are considered cost-effective for major depression, dosage adjustments may be necessary when therapy starts. In the authors' study, patients undergoing dose titration of SSRIs used more medical resources and spent more days receiving a subtherapeutic dose than comparable controls not undergoing dose titration.
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P&T® Journal contents for August 2010
Expenditures Associated with Dose Titration at Initiation of Therapy in Patients with Major Depressive Disorder
A Retrospective Analysis of a Large Managed Care Claims Database
The Widespread Use of CAM and the Need for Better-Informed Health Care Professionals to Provide Patient Counseling
Pharmacists and physicians are in an ideal position to counsel patients on the use of dietary supplements and CAM, but many currently lack the formal training needed to help the growing number of people who wish to use these treatments. Standards have been issued to guide health care professionals, but more initiatives are needed.
American Society of Clinical Oncology, 2010 Annual Meeting and Rose Bengal: From a Wool Dye to a Cancer Therapy
Topics include medications for chronic myelogenous leukemia, melanoma, multiple myeloma, breast cancer, renal cell carcinoma, and lung cancer. The centuries-old history of rose bengal, a promising agent for melanoma, is also presented.
Cabazitaxel (Jevtana) injection for hormone-refractory prostate cancer, aztreonam inhalation solution (Cayston) for improving respiratory symptoms in cystic fibrosis, and denosumab (Prolia) for postmenopausal women with osteoporosis are discussed.