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P&T® Journal contents for May 2008
Drug Utilization Evaluation
The injectable agent daptomycin, when prescribed according to approved guidelines, can be a welcome option for treating some multiresistant, gram-positive infections that have become increasingly prevalent.
Medicaid patients who continued with their initial MI-preventive therapy (beta blockers, calcium-channel blockers, or statins) after a heart attack were more likely to avoid re-infarction and death.
Presentations cover comparisons of ezetimibe/simvastatin (Vytorin) versus Zocor alone for reducing cholesterol; amlodipine/atorvastatin (Caduet) for preventing myocardial ischemia; extended-release niacin/laropiprant (Cordaptive) for lowering lipid levels; and bivalirudin (Angiomax) versus unfractionated heparin for reducing bleeding after coronary procedures.
Topics include bendamustine (Treanda) for chronic lymphocytic leukemia, hepatitis B immune globulin (HepaGam B) to prevent hepatitis B infection following liver transplantation, and a fibrin sealant (Artiss) used in skin graft surgery for burn patients.