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P&T® Journal contents for August 2006


Health Care & Law
Is the traditional randomized controlled trial on the way out? Efforts are under way to promote a new trial design, known as the adaptive trial.
Robert I. Field, JD, MPH, PhD
Meeting Highlights
A regimen of insulin glargine (Lantus) and insulin glulisine (Apridra) is compared with carbohydrate counting to lower glycosylated hemoglobin levels; colesevelam (Welchol), a lipid-lowering agent, benefits glycemic control; and an oral agent, vildagliptin (Galvus), targets pancreatic islet dysfunction.
Reuben B. David
Meeting Highlights
Aliskiren (Rasilez) in combination with hydrochlorothiazide is beneficial for uninterrupted blood pressure control over 24 hours, and valsartan (Diovan) is used for reducing high-sensitivity C-reactive protein levels.
Walter Alexander
Continuing Education Credit
Older and newer agents, as well as nonpharmacological options, are reviewed along with a discussion of urinary incontinence, bladder physiology, and patient education.
George DeMaagd, PharmD, BCPS, and Jeffrey D. Geibig, PharmD


David Nash, MD, MBA, discusses an experimental concept in which an “unsales” force would use evidence-based tools in an effort to encourage doctors to focus on lowering drug costs in Pennsylvania (e.g., by prescribing generic drugs).
David Nash, MD, MBA
Prescription: Washington
Stephen Barlas comments on the pressure to increase the number of generic versions of brand-name drugs and one of the constraints facing the FDA, namely Citizen Petitions.
Stephen Barlas
Medication Errors
Matthew Grissinger, RPh, FASCP, examines the inappropriate use of IV sterile water.
Matthew Grissinger, RPh, FASCP
P&T presents the latest studies and information about FDA approvals, drug indications, industry updates, and new devices.
Drug Forecast
The authors review a drospirenone/estradiol combination (Angeliq) to treat menopausal symptoms.
Nasya Ezell, PharmD Candidate, Alicia Hardy, PharmD Candidate, Marlon Honeywell, PharmD, Angela Singh, PharmD, Jessica Warthen, PharmD, and Patty Ghazvini, PharmD