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Chronic Constipation: Overview and Treatment Options

Ashok K. Tuteja, MD, MPH, and Joseph E. Biskupiak, PhD, MBA
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Although chronic constipation is a common digestive complaint in North America, physicians and patients have very different definitions of this disorder. The authors discuss the three pathophysiological subtypes; complications; pharmacological therapies and their limitations; as well as the potential impact on quality of life and the economy.