Few options have been available for these patients
Company accepts independent annual review of its Medicaid drug rebate practices
Longer-acting GLP-1 diabetes drug reports strong results in Sustain-7 trial
Damage to the joint may be “partly preventable,” researchers say
Policy linked to newly updated requirements for government employee ID cards
Drug-makers utilizing this strategy to better understand the value of their products
Analysis finds that the prescribing disparity is greatest among general practitioners
Scientists’ contributions “revolutionized biomedical research”
Such suits are seeking to holding pharma partially accountable for the opioid epidemic
Products manufactured by PharmaTech were sold by three firms


SIRT for Liver Cancer: Similar Efficacy, Less Toxicity Than Sorafenib

Valérie Vilgrain, MD, of Hôpital Beaujon Service de Radiologie in Paris, describes results of the SARAH trial. Selective internal radiation therapy provided efficacy similar to sorafenib for hepatocellular carcinoma but with considerably fewer adverse events.

European Association for the Study of the Liver International Liver Congress, April 2017

P&T August 2017
Table of Contents


Pharmaceutical industry sectors are at odds as the Food and Drug Administration seeks to define “interchangeability” for biosimilars. The battle lines vary by topic, but biosimilar marketers, health plans, and drugstores are generally urging lower hurdles.
Despite dramatic breakthroughs, obstacles remain for the field of immunotherapy in cancer. These include the inability to predict treatment efficacy and patient response; the need for improved biomarkers; the development of resistance to immunotherapies; the lack of optimized clinical study designs; and high costs. Are solutions in sight?
As interest grows in the potential impact of population health strategies, a recognized leader in the field—the founding dean of the Jefferson College of Population Health—explains key concepts and the role for this approach in safety, efficacy, and costs.
Stewardship programs that ensure proper use of antimicrobials translate to improved patient outcomes. The authors describe the development of an antibiotic stewardship program at a facility with consultant-based infectious disease services.
Meeting Highlights
Notable American Society of Clinical Oncology sessions focused on prostate cancer, non–small-cell lung cancer, and hepatocellular carcinoma. Subjects at the European Congress of Rheumatology included rheumatoid arthritis and axial spondyloarthritis.


Medication Errors
Diluting IV drugs in patient-care areas adds undue risk
FDA delays drug-tracking pilot programs
Approvals, new indications, regulatory activities, and more
Naldemedine (Symproic) for opioid-induced constipation; deutetrabenazine (Austedo) for chorea associated with Huntington’s disease; and infliximab-abda (Renflexis), a Remicade biosimilar, for the treatment of Crohn’s disease, rheumatoid arthritis, and other diseases.
Drug Forecast
Probuphine (buprenorphine) subdermal implants for the treatment of opioid-dependent patients