BREAKING NEWS

PTCommunity News

Sprycel Approved for Type of Newly Diagnosed Pediatric Leukemia
First and Only Second-Generation TKI for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
World-First Device Smaller Than Pea Treats Premature Babies, Newborns With Heart Openings
Potential Life-Saving Device Can be Implanted in 2-LB Babies
FDA Approves Cabometyx for Patients With Aggressive Liver Cancer
New Therapy for Patients With HCC Who Previously Received Nexavar
Zanubrutinib Gets Breakthrough Therapy Designation for Mantle Cell Lymphoma
Aggressive Disease Represents Around 6% of All New Cases of NHL
SEG101 Gets Breakthrough Therapy Status for VOC Prevention in Sickle Cell Disease
New Therapy Could Prevent Painful, Unpredictable Pain Crises
Newly Diagnosed Cancer Patients May Have Greater Risk of Shingles
Study Reveals Having Any Cancer Type Increases Risk by 40 Percent
Caplacizumab Accelerates Platelet Count Normalization in Adults With aTTP
Relief for Patients With Life-Threatening Blood-Clotting Disorder
SM08502 Receives Orphan Drug Designation for Pancreatic Cancer
Data from Phase 1 Study Expected by Summer of 2019
Ultomiris for Adults With Rare, Life-Threatening Blood Disease
Less Burdensome Therapy for Patients With Paroxysmal Nocturnal Hemoglobinuria

P&T December 2018
Table of Contents

Features

Health Care Price Transparency Initiatives Are All the Rage
But Burgeoning Efforts Suffer from Myriad Shortcomings
Americans worry more about the cost and availability of health care than any other major societal issue. Clarity in treatment costs could help alleviate stress.
Health Care & Law
Use of Regulations, Laws, Standards, and Best Practices When Prosecuting and Defending Hospitals in Drug Injury Lawsuits
The authors underscore the importance of understanding standards and procedures as they discuss two lawsuits that arose from drug injury.
Case Report
Reversal of Dabigatran Bleeding and Coagulopathy Using Idarucizumab in a Patient With Acute Kidney Injury
After being treated with idarucizumab, coagulation parameters in a patient with AKI reverted to normal within 24 hours.
Pipeline Plus
Promising Multiple Sclerosis Agents In Late-Stage Development
Developing drugs with enhanced safety profiles and improving treatment affordability are vital for patients with MS. The author reviews some encouraging new agents in late-stage development.
The Extraordinary Importance of Sleep
The Detrimental Effects of Inadequate Sleep on Health and Public Safety Drive an Explosion of Sleep Research
New sleep deprivation studies confirm the relationship between inadequate sleep and a wide range of disorders, such as hypertension, obesity and type-2 diabetes, cardiovascular disease, impaired immune functioning, and more.
A Bitter Pill to Swallow: Why Medication Safety Is Critical in Hepatitis C Treatment
Treating patients with HCV provides many opportunities for medication errors to occur. These may involve regimen selection, adherence, dispensing, and drug–drug interactions. The authors offer ten safety recommendations.

Departments

Medication Errors
Partially Filled Vials and Syringes in Sharps Containers Are a Key Source of Drug Diversion
Leftover or improperly discarded drugs are easy prey for diversion and are fueling the opioid abuse epidemic. ISMP offers safe practice recommendations to prevent drug misuse.
Prescription: Washington
P&T Committees Get New Leeway to Control Part C and Part D Drug Costs
As the door opens to more step therapy and indication-based formularies, P&T committees must walk a fine line between managing treatment costs and providing access to critical drugs.
Drug and Device News December 2018
Approvals, new indications, regulatory activities, and more
Pharmaceutical Approval Update December 2018
Mulpleta (lusutrombopag) for thrombocytopenia; ajovy (fremenezumab-vfrm) for migraine; takhzyro (lanadelumab-flyo) for hereditary angioedema attacks
Drug Forecast
Ertugliflozin (Steglatro): A New Option for SGLT2 Inhibition
Steglatro (ertugliflozin) for glycemic control in adults with type-2 diabetes mellitus
Research Briefs December 2018

Industry announcements

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