BREAKING NEWS

Moderates balk at dropping coverage for pre-existing conditions
Doctors spend too much time facing computers instead of patients, HHS secretary says
First new liver cancer clearance in nearly a decade
House vote may come soon
Commitment aimed at avoiding government shutdown
Patients spend their families into bankruptcy for a few months of life
Winning hospitals achieve shorter ED wait times
Hospitals penalized for factors beyond their control, authors say

P&T April 2017
Table of Contents

Features

As legislation is drafted to replace Obamacare, pharmaceutical issues—including controlling drug prices, expanding or contracting drug access, and incentivizing the development of generic drugs—are expected to be at the forefront of debate.
The authors explore efficacy and safety outcomes in multiple degrees of renal impairment when using FDA-approved dosing regimens for enoxaparin and find that a more multitiered dosing strategy appears to be needed.
Using a retrospective chart review, the authors compare the effectiveness of these two methods of administration in intensive care unit patients with septic shock.
While an educational video led to improvements in short-term knowledge, patients did not retain their understanding at one month, suggesting that future studies should evaluate other strategies to improve long-term retention of knowledge.
Pipeline Plus
We present immunotherapies, biosimilars, and molecular-targeted agents in late-stage development for patients with advanced colorectal cancer.
Meeting Highlights
We focus on liver-directed cancer therapy and the role of yittrium-90, as well as one clinician’s controversial position against routine use of opioids for chronic pain.

Departments

Medication Errors
Twelve persistent safety gaffes that need resolution
Prescription: Washington
FDA pleases no one with final guidance on biological and biosimilar naming
Approvals, new indications, regulatory activities, and more
Abuse-deterrent hydrocodone bitartrate (Vantrela ER) for long-term opioid treatment; etelcalcetide (Parsabiv) for secondary hyperparathyroidism in patients with chronic kidney disease on hemodialysis; and deflazacort (Emflaza) for Duchenne muscular dystrophy
Drug Forecast
Flibanserin (Addyi) for female sexual interest/arousal disorder in premenopausal women