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About P&T Journal
Editorial: Sonja Sherritze, Editor
Advertising: Maureen Dwyer Liberti,
    Vice President, Group Publisher

Production: Mary Ellen Curry,
    Director of Production Services

Circulation: Jackie Ott, Circulation Manager

Statement of Purpose
Guidelines for Authors
Editorial Board

Recent Issues

August 2013


Pharmacovigilance Forum

Diphenhydramine and Acute Kidney Injury

Seldom considered to be a drug that causes renal problems, diphenhydramine can have adverse effects in some patients, as illustrated by a case study of a middle-aged veteran. Extra precautions are urged before this medication is prescribed, especially in elderly patients.
Antony Q. Pham, PharmD, BCPS; and Christina Scarlino, PharmD

Evaluating the Appropriate Use of Piperacillin/ Tazobactam In a Community Health System

A Retrospective Chart Review

Noting inappropriate uses of piperacillin/tazobactam at their institution, the authors emphasize the need for antimicrobial stewardship efforts, as well as infection-control practices, to curtail drug resistance, reduce costs, and minimize adverse events.
Punit J. Shah, PharmD; and Kristi L. Ryzner, PharmD, BCPS

Transparency in Evidence Evaluation and Formulary Decision-Making

From Conceptual Development to Real-World Implementation

The authors sought to clarify the relationship between evidence-based medicine and access to drug coverage. They concluded that a structured approach to improving clarity, consistency, and transparency was lacking.
Bonnie B. Dean, MPH, PhD; Kelly J. Ko, PhD; Jennifer S. Graff, PharmD; A. Russell Localio, JD, MA, MPH, MS, PhD; Rolin Wade, RPh, MS; and Robert W. Dubois, MD, PhD

Clinical Outcomes After Conversion From Brand-Name Tacrolimus (Prograf) to a Generic Formulation In Renal Transplant Recipients

A Retrospective Cohort Study

After kidney transplant recipients who received Prograf were switched to generic tacrolimus, most differences in the safety and effectiveness of the medications were not considered clinically relevant.
Kwaku Marfo, PharmD, MPH, BCPS; Samuel Aitken, PharmD; and Enver Akalin, MD


Medication Errors

Shared Metered Dose Inhalers Among Multiple Patients

Can Cross-Contamination Be Avoided?

Sharing metered dose inhalers among patients can lead to cross-contamination.
Matthew Grissinger, RPh, FASCP

Prescription: Washington

Compounding Pharmacy Reform Moves Forward

Senate Bill’s Exemption of Hospital Pharmacies Stirs Debate

A Senate bill that exempts hospital compounding pharmacies from some rules is stirring debate.
Stephen Barlas

New Drugs/Drug News/New Medical Devices

FDA approvals, drug indications, and updates

Pharmaceutical Approval Update

Canagliflozin (Invokana) for type-2 diabetes; denosumab (Xgeva) for giant-cell tumor of bone; and paroxetine mesylate (Brisdelle) for vasomotor symptoms in menopause
Marvin M. Goldenberg, PhD, RPh, MS

Drug Forecast

Phentermine/Topiramate Extended-Release Capsules (Qsymia) for Weight Loss

David J. Lonneman, Jr.; Jose A. Rey, MS, PharmD, BCPP; and Brian D. McKee, PharmD