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About P&T Journal
Editorial: Sonja Sherritze, Editor
Advertising: Maureen Dwyer Liberti,
    Vice President, Group Publisher

Production: Mary Ellen Curry,
    Director of Production Services

Circulation: Jackie Ott, Circulation Manager

Statement of Purpose
Guidelines for Authors
Editorial Board

Recent Issues

August 2006


Health Care and Law

The FDA’s First Moves to Supplant Randomized Controlled Clinical Trials

Is the traditional randomized controlled trial on the way out? Efforts are under way to promote a new trial design, known as the adaptive trial.
Robert I. Field, JD, MPH, PhD

Meeting Highlights

American Diabetes Association

A regimen of insulin glargine (Lantus) and insulin glulisine (Apridra) is compared with carbohydrate counting to lower glycosylated hemoglobin levels; colesevelam (Welchol), a lipid-lowering agent, benefits glycemic control; and an oral agent, vildagliptin (Galvus), targets pancreatic islet dysfunction.
Reuben B. David

Meeting Highlights

Multiple Sclerosis Symposium and American Society of Hypertension

Aliskiren (Rasilez) in combination with hydrochlorothiazide is beneficial for uninterrupted blood pressure control over 24 hours, and valsartan (Diovan) is used for reducing high-sensitivity C-reactive protein levels.
Walter Alexander

Continuing Education Credit

An Overview of Overactive Bladder and Its Pharmacological Management with a Focus on Anticholinergic Drugs

Older and newer agents, as well as nonpharmacological options, are reviewed along with a discussion of urinary incontinence, bladder physiology, and patient education.
George DeMaagd, PharmD, BCPS, and Jeffrey D. Geibig, PharmD



Foot Soldiers for EBM

David Nash, MD, MBA, discusses an experimental concept in which an “unsales” force would use evidence-based tools in an effort to encourage doctors to focus on lowering drug costs in Pennsylvania (e.g., by prescribing generic drugs).
David Nash, MD, MBA

Prescription: Washington

Pressure Builds to Untie the FDA’s Hands on Generics: High Drug Prices Still Fuel Public–Hence Political–Pressure

Stephen Barlas comments on the pressure to increase the number of generic versions of brand-name drugs and one of the constraints facing the FDA, namely Citizen Petitions.
Stephen Barlas

Medication Errors

Water, Water, Everywhere, but Please Don’t Give IV

Matthew Grissinger, RPh, FASCP, examines the inappropriate use of IV sterile water.
Matthew Grissinger, RPh, FASCP

New Drugs/Drug News/New Medical Devices

P&T presents the latest studies and information about FDA approvals, drug indications, industry updates, and new devices.

Drug Forecast

Drospirenone/Estradiol (Angeliq) for the Treatment of Menopausal Symptoms

The authors review a drospirenone/estradiol combination (Angeliq) to treat menopausal symptoms.
Nasya Ezell, PharmD Candidate, Alicia Hardy, PharmD Candidate, Marlon Honeywell, PharmD, Angela Singh, PharmD, Jessica Warthen, PharmD, and Patty Ghazvini, PharmD