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November 2002
Features
Highlights of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
Lawrence M. Prescott, PhD
Pharmaceutical-Approval Update
Pharmaceutical-Approval Update: Oncology
Marvin M. Goldenberg, PhD, describes new treatments for colorectal, breast, and advanced prostate cancer.
Marvin M. Goldenberg, PhD
Step-Down Treatment of Uncomplicated Gastroesophageal Reflux Disease in Patients Taking Twice-Daily Lansoprazole
It is possible to safely reduce the dose of medication for patients with GERD.
Cameron C. Lindsey, PharmD, Maqual R. Graham, PharmD, and Lauri A. Witt, PharmD
A Prospective Study of Antibiotic Cost Containment in a University Teaching Hospital over a 13-Year Period
A unique antibiotic monitoring program has succeeded in reducing costs.
Arpi G. Kuyumjian, PharmD, Jerome F. Levine, MD, Peter A. Gross, MD, and Antonia Lo Presti, MD
CE
The Impact of NSAID Selection on Gastrointestinal Injury and Risk for Cardiovascular Events: Identifying and Treating Patients at Risk
New COX-1/COX-2 NSAIDs relieve pain with less gastrointestinal damage than past pain relievers but may increase the risk of cardiovascular injury.
Richard L. Ruffalo, MD, PharmD, Robert L. Jackson, MD, and Joshua J. Ofman, MD, MSHS
A Clinician’s Guide to the Selection of NSAID Therapy
The authors review the potential gastrointestinal and cardiovascular risks posed by COX-1/COX-2 NSAIDs.
A. Mark Fendrick, MD, and Susan M. Garabedian-Ruffalo, PharmD
Guest Commentary
The Road Not Taken: Changing Physician-Prescribing Behaviors
The difficulty in educating professionals who prescribe medications is not unlike the challenge of fixing a dangerous road.
Peter Teichman, MD, MPA
Departments
Editorial
National Drug and Therapeutic Index
Editor-in-Chief David Nash discusses the National Drug and Therapeutic Index.
David B. Nash, MD, MBA
Medication Errors
Sample Medications: Safe Management Is a Difficult but Necessary Process
Precautions must be taken when sample medications are dispensed.
Matthew Grissinger
Drug News
New Drugs/Drug News
The latest information about approvals, indication changes, industry updates, and news from the FDA.
Prescription Washington
Government’s Draft Guidelines on Drugs Are Murky At Best
Mr. Barlas discusses the ambiguity of the new federal guidelines for PBMs.
Stephen Barlas
Drug Forecast
Novel Treatment of Allergic Asthma and Seasonal Allergic Rhinitis: Focus on Omalizumab (Xolair®)
Omalizumab is being touted as a new treatment for patients with allergic disorders.
Boris Nogid, PharmD, and Timothy S. McCall, RPh
P&T Snapshot
NSAID Usage in U.S. Hospitals
