Valchlor (Mechlorethamine) Antifungal Gel Launched in U.S.
First FDA-approved topical formulation of mechlorethamine (November 18)
Valchlor (Actelion Ltd.), the first FDA-approved topical formulation of mechlorethamine (commonly known as nitrogen mustard), is now available for patients in the U.S.
The gel, which is applied topically once a day, is an alkylating drug indicated to treat patients with stages IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL) who have received prior skin-directed therapy.
Valchlor (mechlorethamine) gel 0.016% will be distributed in the U.S. by Accredo Specialty Pharmacy.
Mycosis fungoides is the most common type of cutaneous T-cell lymphoma, a rare form of non-Hodgkin's lymphoma. In the U.S., approximately 20,000 patients are currently diagnosed with stage IA-IB MF-CTCL, qualifying it as a rare or orphan disease.
Source: Actelion Ltd.; November 18, 2013.