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P&T News
January 23
Paper-clip-sized implant inserted in upper thigh
Agency’s decision expected in March
Opioid exposure during pregnancy increases risk of birth defects
Mid-stage data show superiority over doxorubicin
Younger population more likely to be diagnosed with advanced disease, authors say
January 22
First IL-17A antagonist for moderate-to-severe plaque psoriasis
Scripps researchers recognize importance of molecular ‘handed-ness’
XRCC2 mutation may explain resistance to platinum-based therapy
Penalties wipe out rewards
Patient wears small, external insulin pump
January 21
Case could block doctors and hospitals from seeking higher rates
Reduced competition is part of the problem, expert says
Low-income families have greatest concern
Vaccine protects against 70% of cervical cancers
Product could be on the market by 2017
January 20
Common disease kills more people each day than Ebola, expert says
Experts review the good, the bad, and the doubtful
Drugs have to keep up with ‘genomic drift’
Novel approach may lead to next generation of better, safer anesthetic agents
Risk of relapse reduced by half compared with placebo
January 19
New formulation improves on once-monthly Invega Sustenna
NIH study finds most older people use alcohol-interactive medications
Mid-stage data support treatment’s immunostimulatory mechanism of action
Polymer nanoparticles release targeted drug molecules
Global cost could reach $70 trillion over next decade
January 16
Such products, defined in the guidance, do not require FDA oversight
The vaccine cuts the risk of having to visit a doctor by 23%
Federal judge approves consent decree with California firm that failed to follow regulations
Benefit shown in cases of wild-type RAS disease
Initiation of registrational studies planned for this year
January 15
Philadelphia team works with GSK to develop cure
Patients are being injected with nonsterile products
Study evaluates mesenchymal precursor cell product
Broadly neutralizing antibodies may hold the key
Treatment reduces thrombotic events in patients with heart attack history
January 14
But continued improvements needed
Electrical stimulation blocks nerve activity between brain and stomach
Pharmacy benefit manager pits drug-makers against each other
ACP addresses health information technology and informatics
System combines reporting, testing, and enforcement rules
January 13
Formulary managers reap benefits of price war
Hives reported in mid-stage trial
Position paper cites lack of decision support for chronic pain management
Intrinsic biologic differences account for variations, study finds
Commercial licensing expected by second quarter of 2015
January 12
Findings spur new research into treatments for gene-related brain diseases
Treatment provides survival benefit compared with chemotherapy
Test identifies critical viral targets in one assay
Doctors seek higher payments
First treatment to provide 16 continuous hours of the drug combination