F. Randy Vogenberg RPh, PhD
Judith Gomes

The health care environment is undergoing rapid change, posing an increasing number and mix of challenges for health care professionals. As the health care system evolves, the pharmacy and therapeutics (P&T) committee is adapting in step.

Who would have thought that by 2014, P&T committees would be dealing with chronic drug shortages and becoming involved in ethical discussions on medication rationing? In the past decade, the committee’s role in hospitals, payer organizations, and other entities has also evolved to meet the needs of a market that has changed with the implementation of the Affordable Care Act (ACA); the emergence of large, robust health care systems; and the proliferation of biotechnology-based drugs, diagnostic tests, and devices.

Matthew Grissinger RPh, FASCP

Problem: We are aware of numerous reports of serious errors associated with the misadministration of insulin. These events have involved various types of practitioners, including physician house officers (HOs), nurses, and a pharmacist. Human error (e.g., mental slips, lapses, forgetfulness) associated with insulin dose measurement and hyperkalemia treatment was the predominant proximate cause of these events; most of the human errors were associated with knowledge deficits regarding insulin concentration (specifically that “U-100” means the concentration is 100 units per mL), the differences between insulin syringes and other parenteral syringes, and a perceived urgency with treating hyperkalemia.

Kunj Gohil PharmD, RPh

Naltrexone/bupropion (Contrave) for weight management; pembrolizumab (Keytruda) for melanoma; dolutegravir/abacavir/lamivudine (Triumeq) for HIV-1; and immune globulin infusion 10% (human) with recombinant human hyaluronidase (Hyqvia) for primary immunodeficiency


From Sovaldi to Ebola: A Wide-ranging Interview with Dr. David Nash

A leading authority on population health, Dr. David Nash is optimistic about the future of disruptive innovation to improve healthcare in the U.S. The interview was conducted by P&T Editor Sonja Sherritze.


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