BREAKING NEWS

Hospitals would receive quality-adjusted pricing for heart attack and bypass care
Growing percentage of patients combine drugs without physician’s knowledge
Product is extended-release formulation of Viekira Pak
Pregnant women are at risk of exposure from partners of either gender
Celgene won’t pursue indication for diffuse B-cell lymphoma
New research could help identify at-risk individuals
Agency cites manufacturing concerns
Virological suppression is similar to that of Complera and Atripla
Tramiprosate will target patients with specific genes

P&T July 2016
Table of Contents

Features

A new test model starting in five regions in 2017 seeks better integration of pharmacists into the Medicare Part D Medication Therapy Management program, which has severely underperformed since the Part D benefit took effect in 2006.
Childhood vaccination is one of the most effective public health strategies to control and prevent disease, but some parents decline or delay vaccinating their children. A variety of measures have been suggested to overcome vaccine noncompliance.
National treatment guidelines for bacterial meningitis were published in 2004, but no assessment of their use has been reported. In retrospective chart reviews at two hospitals, recommended antibiotic regimens were given to 52.6% of the 38 patients.
In a retrospective review, the prevalence of delirium did not differ among intensive care unit patients who received either dexmedetomidine or propofol alone for 24 hours or more. Propofol was linked with more coma and shorter hospital stays.
Meeting Highlights
We report on key Digestive Disease Week sessions that focused on hepatitis C virus and Clostridium difficile infection, colonoscopy preparation, irritable bowel syndrome, and Crohn’s disease. We also review major American Society of Clinical Oncology sessions on breast, pancreatic, ovarian, skin, and brain cancers and multiple myeloma.

Departments

Medication Errors
We all have a role in preventing fentanyl patch tragedies
Prescription: Washington
HHS walks a middle ground in final nondiscrimination rule
Approvals, new indications, regulatory activities, and more
Defibrotide sodium (Defitelio) for hepatic veno-occlusive disease; emtricitabine/tenofovir alafenamide (Descovy) for human immunodeficiency virus infection; and infliximabdyyb (Inflectra) for Crohn’s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis
Drug Forecast
Brexpiprazole (Rexulti): a new monotherapy for schizophrenia and adjunctive therapy for major depressive disorder